产品货号：
Z16964
中文名称：
Hamartin/TSC1抗体
英文名称：
Anti-Hamartin/TSC1 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Hamartin/TSC1 Antibody |
| 指标别名 | Hamartin;KIAA0243;LAM;TSC;TSC1;tuberous sclerosis 1;Tuberous sclerosis 1 protein |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC,ICCIF,FCM,ELISA |
| 基因名称 | TSC1 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | E.coli-derived human Hamartin/TSC1 recombinant protein (Position:M1-H618). |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Hamartin also known as tuberous sclerosis 1 is a protein that in humans is encoded by the TSC1 gene.It is mapped to 9q34.13.This peripheral membrane protein was implicated as a tumor suppressor.It forms a complex with TSC2 that regulates mTORC1 signaling and may be also involved in vesicular transport and docking.Hamartin and TSC2 have critical roles in neuronal polarity,and that a common pathway regulates polarization and growth in neurons and cell size in other tissues.Hamartin is a growth inhibitory protein whose biologic effect is probably dependent on its interaction with tuberin.It also can affect cell proliferation via deregulation of G1 phase.Loss or perturbation of Hamartin function leads to loss of adhesion to the cellular matrix and initiates the development of TSC hamartomas. |
| Uniprot ID | Q92574 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P) and ICC. |
| 基因名全称 | TSC complex subunit 1 |
| 蛋白名全称 | Hamartin |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Immunocytochemistry/Immunofluorescence (ICC/IF) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells ELISA 1:100～1000 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
| Gene ID | 7248 |
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